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Bone Marrow Transplant

What Is a Bone Marrow Transplant?

Bone marrow is the soft, spongy tissue found inside your bones where blood cells are produced. When marrow is damaged by disease, chemotherapy, or radiation, it can no longer make enough healthy blood cells. A bone marrow transplant replaces the unhealthy marrow with healthy stem cells, which then travel to the bone marrow and begin producing normal blood cells again.

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Types of Bone Marrow Transplants

  • Autologous Transplant Uses the patient's own stem cells, collected and stored before high-dose chemotherapy or radiation, then reinfused afterward.
  • Allogeneic Transplant Uses stem cells from a matched donor — often a sibling, unrelated donor, or umbilical cord blood — to replace unhealthy marrow with donor-derived healthy cells.
  • Haploidentical (Half-Matched) Transplant Uses stem cells from a partially matched family member, expanding transplant options for patients without a fully matched donor.

Conditions We Treat

  • Leukemia (acute and chronic)
  • Lymphoma (Hodgkin and non-Hodgkin)
  • Multiple myeloma
  • Aplastic anemia
  • Myelodysplastic syndromes (MDS)
  • Sickle cell disease
  • Thalassemia
  • Certain inherited immune and metabolic disorders

The Transplant Journey

1. Evaluation and Planning

Our team conducts a comprehensive assessment, including blood tests, imaging, organ function tests, and donor matching (if applicable), to determine the best treatment approach for you.

2. Conditioning Therapy

Before transplant, patients undergo chemotherapy and/or radiation to destroy diseased cells and prepare the body to accept new stem cells.

3. Stem Cell Infusion

Healthy stem cells — from the patient or a donor — are infused into the bloodstream through a central line, much like a blood transfusion.

4. Engraftment and Recovery

Over the following weeks, the new stem cells travel to the bone marrow and begin producing healthy blood cells. Patients are closely monitored for infection, and blood counts are tracked daily.

5. Long-Term Follow-Up

Recovery continues for months after discharge. Our team provides ongoing monitoring, supportive care, and guidance to help patients return to daily life safely.

Why Choose Our Transplant Program

  • Experienced Multidisciplinary Team — Hematologists, oncologists, transplant surgeons, nurses, and social workers collaborate on every case.
  • Advanced Donor Matching — Access to national and international donor registries and cord blood banks.
  • Comprehensive Supportive Care — Nutrition support, infection prevention, psychological counseling, and rehabilitation services.
  • Personalized Treatment Plans — Every patient's protocol is tailored to their diagnosis, health status, and donor availability.
  • Dedicated Transplant Unit — Specialized, infection-controlled inpatient facilities designed for transplant recovery.

Risks and Considerations

Like any major medical procedure, bone marrow transplant carries risks, including infection, graft-versus-host disease (in allogeneic transplants), and organ complications. Our team works closely with each patient to explain risks, set realistic expectations, and provide close monitoring throughout treatment to minimize complications.